of circulation, their primary "nolvadex and testosterone" The superficial pain happens эпикритической, or early, sharp, fast, localised, warning and быстроадаптирующейся (for example, a prick a needle under a nail), and also протопатической which follows the early. It is the late, stupid, non-local, long, reminding and not adapting pain. In the course of evolution special response of an organism to action пирогенных factors - a fever (пирексия, heat, a fever) is developed. It is the protective mechanism directed against viruses, microorganisms and alien substances. On degree of lifting of temperature distinguish: субфебрильную a fever (rise in temperature to 38 °), moderated (38-39 °) and excessive (above 41 °). The fever is a condition of an organism at which the thermoregulation centre stimulates body rise in temperature. Этодостигается перестраиванием the mechanism of "an adjusting point» on higher, than in norm, regulation temperature. The group нейронов, carrying out the analysis of current average body temperature and its comparison with the new established value, perceives normal temperature of a kernel of a body as low. The mechanisms which are making active теплопродукцию (increase терморегуляционного a tone of muscles, a muscular shiver) and reducing intensity теплоотдачи (narrowing of vessels of a surface of a body, acceptance of the pose reducing the area of contact of a surface of a body with environment) join. Though it is subjective at this time the person the fever, actually body temperature feels raises and soon reaches the new, established level of regulation. The equilibration of processes of development and heat return from this point on begins. As a result a shiver as one of the most effective ways теплопродукции, disappears, superficial vessels extend, the temperature of a skin and superficial fabrics raises. Since the moment when in an organism the balance интенсивностей теплопродукции and теплоотдачи is reached, there is a sensation of heat and the fever disappears. Transition of "an adjusting point» on higher level results from action on corresponding group нейронов преоптической area гипоталамуса эндогенных пирогенов - the substances causing lifting of body temperature. To them carry: полисахариды yeast, липотейхоевую acid грамположительных microbes, albuminous экзотоксины microbes, various allergens, лектины, containing in vegetative products, activation products комплемента, complexes an antigene-antibody, products of disintegration of own fabrics after their receipt in blood. All of them in itself are not capable to cause a fever, therefore them name экзогенными пирогенами. Having got to blood, they activate liberation from leukocytes эндогенного пирогена (лейкоцитарного пирогена) - интерлейкина. Development эндогенных пирогенов occurs in нейтрофилах, эозинофилах, моноцитах, гистиоцитах, cages of Kupfera. Эндогенными пирогенами are пептиды: интерлейкины in forms and and р, the factor некроза tumours, a-interferon and others. 3. The zvukovosprinimajushchy device (an internal ear).
I’ve heard it said that marketing is simple; tell people what you do, and tell them over and over again. For the average small business, I think that marketing should be that simple. Small-business professionals wear multiple hats and their demands require simple and effective execution.
However, marketing is only this simple with one key piece in play: you have to know what you really do and why a prospective customer should come to you. Knowing what you REALLY do can lead to simple and easy marketing messages and will help dictate what types of marketing you do. Here are a couple of questions to ask.
What makes my business different? – What do you do differently than your competition? Often times, it is what you do different, unique, or above and beyond that is the best indicator of “what you do”.
What line of business am I the best at? – Often times, one company can have many lines of business. For instance, a plumber could provide plumbing repair, plumbing maintenance, emergency plumbing services, plumbing for new homes, etc. What this plumber does best may be the message that he/she should share.
What would my loyal customers say about me? – It has been said that your brand is no longer what you say it is, it is what your customers say it is. In terms of marketing, I would say that the same thought applies to “what you do”. Ask your most loyal customers what they think about your business. They’re loyal for a reason. Find out why.
Simple marketing can lead to better decisions, allocation of funds and results. Invest a little time in determining what it is that you do, and start telling people. Once you start telling them, do it over and over again.